Structure of PDB 9fxj Chain B

Receptor sequence

>9fxjB (length=326) Species: 9606 (Homo sapiens) [Search protein sequence]

SAWPEEKNYHQPAILNSSALRQIAEGTSISEMWQNDLQPLLIERYPGSPG
SYAARQHIMQRIQRLQADWVLEIDTFLSQTPEGERSFSNIISTLNPTAKR
HLVLACHYDSKYFSHWNNRVFVGATDSAVPCAMMLELARALDKKLLSLKT
VSKPDLSLQLIFFDGEEAFLHWSPQDSLYGSRHLAAKMASTPHPPGARGT
SQLHGMDLLVLLDLIGAPNPTFPNFFPNSARWFERLQAIEHELHELGLLK
DHSLEGRYFQNYSYGGVIQDDHIPFLRRGVPVLHLIPSPFPEVWHTMDDN
EENLDESTIDNLNKILQVFVLEYLHL

3D structure

PDB

9fxj Metal Ion Binding to Human Glutaminyl Cyclase: A Structural Perspective.

Chain

Resolution

3.06 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	CO	B	D159 E202 H330	D126 E167 H295
BS02	PBD	B	D159 E201 W207 D248 Y299 I303 Q304 F325 W329 H330	D126 E166 W172 D213 Y264 I268 Q269 F290 W294 H295

External links

PDB	RCSB:9fxj, PDBe:9fxj, PDBj:9fxj
PDBsum	9fxj
PubMed	39125848
UniProt	Q16769\|QPCT_HUMAN Glutaminyl-peptide cyclotransferase (Gene Name=QPCT)

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