Structure of PDB 9fhe Chain B

Receptor sequence
>9fheB (length=301) Species: 9606 (Homo sapiens) [Search protein sequence]
GLVPRGSQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSC
TVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSS
CCIINNSNGNRTIVLHDTSLPDVSATDFEKVDLTQFKWIHIEGRNASEQV
KMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAK
HLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPP
PRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGI
V
3D structure
PDB9fhe Discovery of BI-9787, a potent zwitterionic ketohexokinase inhibitor with oral bioavailability.
ChainB
Resolution2.313 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1ICK B A224 A226 E227 V250 T253 G257 C289 A227 A229 E230 V253 T256 G260 C292
External links
PDB RCSB:9fhe, PDBe:9fhe, PDBj:9fhe
PDBsum9fhe
PubMed39179180
UniProtP50053|KHK_HUMAN Ketohexokinase (Gene Name=KHK)

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