Structure of PDB 9fhd Chain B

Receptor sequence
>9fhdB (length=302) Species: 9606 (Homo sapiens) [Search protein sequence]
SGLVPRGSQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNS
CTVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPS
SCCIINNSNGNRTIVLHDTSLPDVSATDFEKVDLTQFKWIHIEGRNASEQ
VKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVA
KHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFP
PPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDG
IV
3D structure
PDB9fhd Discovery of BI-9787, a potent zwitterionic ketohexokinase inhibitor with oral bioavailability.
ChainB
Resolution1.845 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1ICK B A224 A226 G229 V250 G257 C289 A228 A230 G233 V254 G261 C293
External links
PDB RCSB:9fhd, PDBe:9fhd, PDBj:9fhd
PDBsum9fhd
PubMed39179180
UniProtP50053|KHK_HUMAN Ketohexokinase (Gene Name=KHK)

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