Structure of PDB 9f45 Chain B |
>9f45B (length=2192) Species: 9606 (Homo sapiens) [Search protein sequence] |
SNVSVLQQFASGLKRAKAAKELQHYVTMELRSTRFYDQLNHHIFELERKG GILAIASLIGVEGGNATRIGRFANYLRNLLPSNDPVVMEMASKAIGRLAM AGDTFTAEYVEFEVKRALEWLEGRRHAAVLVLRELAISVPTFFFQQVQPF FDNIFVAVWDPKQAIREGAVAALRACLILTTQRWYRHTFEEAEKGFDDDR IHGALLILNELVRISSMEGERLREEMEEIMGFGTKPRHITPFTLVESRCC RDLMEEKFDQVCQWVLKCSLIQMTILNLLPRLAAFRPTQYLQDTMNHVLS CVKKEKERTAAFQALGLLSVAVRSEFKVYLPRVLDIIRAALPPKVDATVF TCISMLARIQQDIKELLEPMLAVGLSPALTAVLYDLSRQIPQLKKDIQDG LLKMLSLVLMHDVGSITLALRTLGSFEFELTQFVRHCADHFLNSEHKEIR MEAARTCSRLLTPSVSQTAVQVVADVLSKLLVVGITDPDPDIRYCVLASL DERFDAHLAQAENLQALFVALNDQVFEIRELAICTVGRLSSMNPAFVMPF LRKMLIQILTELEHSGIGRIKEQSARMLGHLVSNAPRLIRPYMEPILKAL ILKLKDPNPGVINNVLATIGELAQVSGLEMRKWVDELFIIIMDMLQDSSL LAKRQVALWTLGQLVASTGYVVEPYRKYPTLLEVLLNFLKTEQNQGTRRE AIRVLGLLGALDPYKHKVNIEMLVNMGNLPLDEFYPAVSMVALMRIFRDQ SLSHHHTMVVQAITFIFKSLGLKCVQFLPQVMPTFLNVIRVCDGAIREFL FQQLGMLVSFVKSHIRPYMDEIVTLMREFWVMNTSIQSTIILLIEQIVVA LGGEFKLYLPQLIPHMLRVFMHDNSPGRIVSIKLLAAIQLFGANLDDYLH LLLPPIVKLFDAPEAPLPSRKAALETVDRLTESLDFTDYASRIIHPIVRT LDQSPELRSTAMDTLSSLVFQLGKKYQIFIPMVNKVLVRHRINHQRYDVL ICRIVKGYTLSTINLQKAWGAARRVSKDDWLEWLRRLSLELLKDSSSPSL RSCWALAQAYNPMARDLFNAAFVSCWSELNEDQQDELIRSIELALTSQDI AEVTQTLLNLAEFMEHSDKGPLPLRDDNGIVLLGERAAKCRAYAKALHYK ELEFQKGPTPAILESLISINNKLQQPEAAAGVLEYAMKHFGELEIQATWY EKLHEWEDALVAYDKKMDTNKDDPELMLGRMRCLEALGEWGQLHQQCCEK WTLVNDETQAKMARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVL ALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELE EVIQYKLVPERREIIRQIWWERLQGCQRIVEDWQKILMVRSLVVSPHEDM RTWLKYASLCGKSGRLALAHKTLVLLLGVDPSRQLDHPLPTVHPQVTYAY MKNMWKSARKIDAFQHMQHFVQTMQQQAQHAIATEDQQHKQELHKLMARC FLKLGEWQLNLQGINESTIPKVLQYYSAATEHDRSWYKAWHAWAVMNFEA VLHYKHQNQARDEKKKVTEDLSKTLLMYTVPAVQGFFRSISLSRGNNLQD TLRVLTLWFDYGHWPDVNEALVEGVKAIQIDTWLQVIPQLIARIDTPRPL VGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHNAANKILKNMCEHS NTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLE PLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWD LYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIR IQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLF GLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRD YREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKL LWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGK ILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHT VMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTALNKKAIQIINRVRDK LTGRDFSHDDTLDVPTQVELLIKQATSHENLCQCYIGWCPFW |
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PDB | 9f45 mTORC1 phosphorylates and stabilizes LST2 to negatively regulate EGFR |
Chain | B |
Resolution | 3.74 Å |
3D structure |
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