Structure of PDB 9f3x Chain B

Receptor sequence

>9f3xB (length=792) Species: 573 (Klebsiella pneumoniae)

MEGLTPRMQRLRNHYLTVRPSVSIYRALAFTEVVKANPGMPTILLRAKAF
RHACETAPILIQDDELIVGHPCGKPRAGAFSPDIAWRWVRDELDTMSTRP
QDPFEISEADKKTIREEIVPFWEGRSLDEICEAQYREAGVWAFSGETFVS
DLSYHQINGGGDTCPGYDVLLFTKGMNGIKADAEAHLASLSMENPEDIDR
IYYYKAAIETCEGVVNYARRIAAHARELAAKEQNAQRRAELLTIAEVNEN
VPANPPKTLQEALQSIWTVESLFEIEENQTGLSLGRVDQYCYPMFEADIR
EGRLTHDTALELLQAFIIKCAELMWMSSELGAKYFAGYQPFINLTVGGQK
RSGGDACNDLTYLIMDAVRFVKVYQPSLACRIHNQSPQKYMEKIVDVVKA
GMGFPACHFDDSHIKMMLRKGFDFEDARDYCLMGCVEPQKSGRIYQWTST
GYTQWPIAIEFVLNRGRMVLFDSYQGLDTGDLRDLRTFDEFDAAVKQQIA
HIVRLSAIGTVISQRVHRDVAPKPLMSLLVEGCMESGKDVAAGGAMVNHG
PGLIFSGLATYVDSMAAIRKLVFEEKKYTLEQIRDALLANFEGYEALRRD
CLNAPKYGNDDNYVDQYALDITEWTEKECRKYKMLYSTLSHGTLSISNNT
PIGELTNATPNGRLAWMPLSDGISPTQGADKQGPTAIIKSVSKMNVETMN
IGMVHNFKFLKGLLDTPEGRHGLITLLRTASILGNGQMQFSYVDNEVLKK
AQQEPEKYRDLIVRVAGYSAYFVELCKEVQDEIISRTVIEKF

3D structure

• PDB: 9f3x Towards automated crystallographic structure refinement with phenix.refine.
• Chain: B
• Resolution: 2.7 Å

Enzymatic activity

• Enzyme Commision number: 4.3.99.4: choline trimethylamine-lyase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	A1H9K	B	Y490 D498 T616 F671 F677 C771 E773 T784	Y154 D162 T280 F335 F341 C435 E437 T448

Gene Ontology

Molecular Function

• GO:0003824 catalytic activity
• GO:0016829 lyase activity
• GO:0016840 carbon-nitrogen lyase activity

Biological Process

• GO:0042426 choline catabolic process

Cellular Component

• GO:0005829 cytosol

External links

• PDB: RCSB:9f3x, PDBe:9f3x, PDBj:9f3x
• PDBsum: 9f3x
• UniProt: A0A486V7R5