Structure of PDB 9f1n Chain B

Receptor sequence
>9f1nB (length=126) Species: 9606 (Homo sapiens) [Search protein sequence]
SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVK
LNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNK
PGDDIVLMAEALEKLFLQKINELPTE
3D structure
PDB9f1n First bromodomain of BRD4 in complex with ISOX-DUAL based degrader 46
ChainB
Resolution1.71 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1H9H B W81 P82 L92 N140 D145 I146 M149 W40 P41 L51 N99 D104 I105 M108
External links
PDB RCSB:9f1n, PDBe:9f1n, PDBj:9f1n
PDBsum9f1n
PubMed
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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