Structure of PDB 9f1m Chain B

Receptor sequence
>9f1mB (length=123) Species: 9606 (Homo sapiens) [Search protein sequence]
MNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKL
NLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKP
GDDIVLMAEALEKLFLQKINELP
3D structure
PDB9f1m First bromodomain of BRD4 in complex with ISOX-DUAL based degrader 45
ChainB
Resolution1.90001 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1H80 B W81 P82 F83 Q85 L92 N140 I146 W39 P40 F41 Q43 L50 N98 I104
External links
PDB RCSB:9f1m, PDBe:9f1m, PDBj:9f1m
PDBsum9f1m
PubMed
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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