Structure of PDB 9eq0 Chain B

Receptor sequence
>9eq0B (length=324) Species: 9606 (Homo sapiens) [Search protein sequence]
GPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSE
VFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVK
DPVSRTPALVFEHVNNTDFKTLTDYDIRFYMYEILKALDYCHSMGIMHRD
VKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDY
QMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD
YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLR
YDHQSRLTAREAMEHPYFYTVVKD
3D structure
PDB9eq0 Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric ligand FGJG12
ChainB
Resolution3.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1H6D B L45 P159 H160 V162 M163 I164 I174 M225 L43 P153 H154 V156 M157 I158 I168 M219
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:9eq0, PDBe:9eq0, PDBj:9eq0
PDBsum9eq0
PubMed39067440
UniProtP68400|CSK21_HUMAN Casein kinase II subunit alpha (Gene Name=CSNK2A1)

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