Structure of PDB 9eoc Chain B

Receptor sequence
>9eocB (length=485) Species: 9606 (Homo sapiens) [Search protein sequence]
PTVVVMDVSLSMTRPVSIEGSEEYQRKHLAAHGLTMLFEHMATNYKLEFT
ALVVFSSLWELMVPFTRDYNTLQEALSNMDDYDKTCLESALVGVCNIVQQ
EWGGAIPCQVVLVTDGCLGIGRGSLRHSLATQNQRSESNRFPLPFPFPSK
LYIMCMANLEELQSTDSLECLERLIDLNNGEGQIFTIDGPLCLKNVQSMF
GKLIDLAYTPFHAVLKCGHLTADVQVFPRPEPFVVDEEIDPIPKVINTDL
EIVGFIDIADISSPPVLSRHLVLPIALNSANQIAGKIPNFCVLLHGSLKV
EGMVAIVQLGPEWHGMLYSQKKKSNLMMSLFEPGPEPLPWLGKMAQLGPI
SDAKENPYGEDDNKSPFPLQPKNKRSYAQNVTVWIKPSGLQTDVQKILRN
ARKLPEKTQTFYKELNRLRKAALAFGFLDLLKGVADMLERECTLLPETAH
PDAAFQLTHAAQQLKLASTGTSEYAAYDQNITPLH
3D structure
PDB9eoc Structural basis of the Integrator complex assembly and association with transcription factors.
ChainB
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B S10 S12 T86 S9 S11 T85
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0016180 snRNA processing
GO:0034243 regulation of transcription elongation by RNA polymerase II
GO:0034472 snRNA 3'-end processing
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0032039 integrator complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:9eoc, PDBe:9eoc, PDBj:9eoc
PDBsum9eoc
PubMed38823386
UniProtQ96SY0|INT14_HUMAN Integrator complex subunit 14 (Gene Name=INTS14)

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