Structure of PDB 9enn Chain B

Receptor sequence

>9ennB (length=531) Species: 76867 (Hebeloma cylindrosporum) [Search protein sequence]

ERVGILGAGIGGLYSALILQSLDVPFEIIEASNRVGGRLFTHKFPNGGKY
DYYDVGAMRYPLPKSDDKGNYQPGVMQRVGQLFTYLGMHKQLIPYYFKSN
KSPGFQYFNGVRARIGEGSSFDAPALGINSSLIDIGVTKIVNDAVGPFAQ
ALFDDLQKHTTTGWDDMMKNDAYSTRSYFSFKYLPSPSFGLPSEHFSTRV
INWLETFDKSTGWYDRGLTETVLEAIAFGEVEVDWRCIDGGSHVLPDTIA
AFLHKKGGNAFVMNASVTAIGLENPNKEDSPMVVVAGGQKRKYSHVISTL
PLPVLRTVDLKNSKLDIVQSNALRKLQYGPSIKIGILFKEPWWTTGQDKN
GEKFDLVGGQSYTDLPIRTVVYPSYGVNTNAPSNTLIASYCWTNDAERMG
SLIGTGAATYEEQLEHLVLSNLAAVHNTDYQYLKDRLVDVHSWDWNHNPL
TMGAFAFFGPGDFQDLYTSLNRPAANGKLHFAGEALSVRHAWVVGALDSA
WRAVYNYLYVTDPAKLPKFFELWGKNAEWFE

3D structure

PDB

9enn Crystal structure and enzyme engineering of the broad substrate spectrum L-amino acid oxidase 4 from the fungus Hebeloma cylindrosporum

Chain

Resolution

1.8 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FDA	B	G71 G73 I74 G75 E94 A95 G101 R102 G120 A121 M122 R123 Y124 S333 V334 L367 W512 L517 F522 G550 E551 A558 W559 V560 A563	G7 G9 I10 G11 E30 A31 G37 R38 G56 A57 M58 R59 Y60 S266 V267 L300 W445 L450 F455 G483 E484 A491 W492 V493 A496
BS02	ALY	B	R123 E288 F292 Y457 W459 F522 F524 A558 W559	R59 E224 F228 Y390 W392 F455 F457 A491 W492

External links

PDB	RCSB:9enn, PDBe:9enn, PDBj:9enn
PDBsum	9enn
PubMed	39152524
UniProt	S4S6Z0

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