Structure of PDB 9cts Chain B

Receptor sequence
>9ctsB (length=376) Species: 9606 (Homo sapiens) [Search protein sequence]
TITYTSQVANARLGSFSRLLLCWRGSIYKLLYGEFLIFLLCYYIIRFIYR
LALTEEQQLMFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLP
WPDRLMSLVSGFVEGKDEQGRLLRRTLIRYANLGNVLILRSVSTAVYKRF
PSAQHLVQAGFMTPAEHKQLEKLSLPHNMFWVPWVWFANLSMKAWLGGRI
RDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQVVTVAVYSFFLTC
LVGRQFLNPAKAYPGHELDLVVPVFTFLQFFFYVGWLKVAEQLINPFGED
DDDFETNWIVDRNLQVSLLAVDEMHQDLPRMEPDMYWNKPEPQPPYTAAS
AQFRRASFMGSTFNISLNKEEMEFQP
3D structure
PDB9cts GAD65 tunes the functions of Best1 as a GABA receptor and a neurotransmitter conducting channel.
ChainB
Resolution2.45 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B Q293 N296 D301 D304 Q292 N295 D300 D303
BS02 ABU B R255 F257 P274 F276 T277 R254 F256 P273 F275 T276
BS03 ABU B Y68 Y72 Y67 Y71
External links
PDB RCSB:9cts, PDBe:9cts, PDBj:9cts
PDBsum9cts
PubMed39277606
UniProtO76090|BEST1_HUMAN Bestrophin-1 (Gene Name=BEST1)

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