Structure of PDB 9cmz Chain B

Receptor sequence
>9cmzB (length=284) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence]
IDISNFDFLYVIGKGTYGIVYKALDKKENNFVAIKKIINLNDENYGISKR
ILRELTILQKIKHKNIINLKYVFYGKDIENSCLYLAFEYCDIDLFNLIKK
HNLNIKEIKYIIFELLLALSYFHSNNYIHRDIKPENIFITSEGEIKLGDL
GMSVEKSDHMTPTVVTLWYRAPEILLKSTNYDQKVDIWSLGCLFMELIQG
RPLFPGKNDNTQLELIYLLLGDKDALTTVDKERKDMFPYFEINMLKDAID
DEHTLDLISKMLIYDPNYRISSKEALKHPCFQDI
3D structure
PDB9cmz Crystal Structure of Cdk-related protein kinase 6 (PK6) from Plasmodium falciparum in complex with inhibitor KG2-051
ChainB
Resolution2.45 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1AZE B Y13 I15 V23 A36 F99 Y101 C102 D103 I104 N108 F150 Y10 I12 V20 A33 F87 Y89 C90 D91 I92 N96 F138
Gene Ontology
Molecular Function
GO:0004674 protein serine/threonine kinase activity
GO:0004693 cyclin-dependent protein serine/threonine kinase activity
GO:0005524 ATP binding
Biological Process
GO:0016310 phosphorylation
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016592 mediator complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:9cmz, PDBe:9cmz, PDBj:9cmz
PDBsum9cmz
PubMed
UniProtQ8IDW1

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