Structure of PDB 9cc3 Chain B

Receptor sequence
>9cc3B (length=544) Species: 9606 (Homo sapiens) [Search protein sequence]
LQEQLKIIKKELGLEKDDKDAIEEKFRERLKELVVPKHVMDVVDEELSKL
GLLDNHSSEFNVTRNYLDWLTSIPWGKYSNENLDLARAQAVLEEDHYGME
DVKKRILEFIAVSQLRGSTQGKILCFYGPPGVGKTSIARSIARALNREYF
RFSVGGMTDVAEIKGHRRTYVGAMPGKIIQCLKKTKTENPLILIDEVDKI
GRGDPSSALLELLDPEQNANFLDHYLDVPVDLSKVLFICTANVTDTIPEP
LRDRMEMINVSGYVAQEKLAIAERYLVPQARALCGLDESKAKLSSDVLTL
LIKQYCRESGVRNLQKQVEKVLRKSAYKIVSGEAESVEVTPENLQDFVGK
PVFTVERMYDVTPPGVVMGLAWTAMGGSTLFVETSLRRPQKDGSLEVTGQ
LGEVMKESARIAYTFARAFLMQHAPANDYLVTSHIHLHVPEGATPKDGPS
AGCTIVTALLSLAMGRPVRQNLAMTGEVSLTGKILPVGGIKEKTIAAKRA
GVTCIVLPAENKKDFYDLAAFITEGLEVHFVEHYREIFDIAFPD
3D structure
PDB9cc3 Structural and mechanistic studies on human LONP1 redefine the hand-over-hand translocation mechanism.
ChainB
Resolution3.23 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ADP B Y492 G526 V527 G528 K529 T530 S531 Y661 I669 R710 Y97 G131 V132 G133 K134 T135 S136 Y263 I271 R312
External links
PDB RCSB:9cc3, PDBe:9cc3, PDBj:9cc3
PDBsum9cc3
PubMed38979310
UniProtP36776|LONM_HUMAN Lon protease homolog, mitochondrial (Gene Name=LONP1)

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