Structure of PDB 9bwt Chain B

Receptor sequence
>9bwtB (length=373) Species: 9606 (Homo sapiens) [Search protein sequence]
VQAGSYNLALSYSVGLNEVEDHIKNYRPQCLVLTGPPNFRPALVDFVGTF
TRNLSLMICGHVLIGPHKQRMPELQLIANGHTKWLNKRKIKAFYSDVIAE
DLRRGVQILMQAAGLGRMKPNILVVGFKKNWQSAHPATVEDYIGILHDAF
DFNYGVCVMRMREGLNVEQATTIFQSEQGKKTIDIYWLFDDGGLTLLIPY
LLGRKRRWSKCKIRVFVGGQINRMDQERKAIISLLSKFRLGFHEVHILPD
INQNPRAEHTKRFEDMIAPFRLNDGFKDEATVNEMRRDCPWKISDEEITK
NRVKSLRQVRLNEIVLDYSRDAALIVITLPIGRKGKCPSSLYMAWLETLS
QDLRPPVILIRGNQENVLTFYCQ
3D structure
PDB9bwt Structural bases for Na + -Cl - cotransporter inhibition by thiazide diuretic drugs and activation by kinases.
ChainB
Resolution2.5 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP B L647 G649 R654 V676 L716 G740 K742 N780 L33 G35 R40 V62 L102 G126 K128 N166
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