Structure of PDB 9bhs Chain B

Receptor sequence
>9bhsB (length=297) Species: 9606 (Homo sapiens) [Search protein sequence]
AFRPISVFREANEDESGFTCCAFSARERFLMLGTCTGQLKLYNVFSGQEE
ASYNCHNSAITHLEPSRDGSLLLTSATWSQPLSALWGMKSVFDMKHSFTE
DHYVEFSKHSQDRVIGTKGDIAHIYDIQTGNKLLTLFNPDLANNYKRNCA
TFNPTDDLVLNDGVLWDVRSAQAIHKFDKFNMNISGVFHPNGLEVIINTE
IWDLRTFHLLHTVPALDQCRVVFNHTGTVMYGAMLQAMKSPFGSSFRTFN
ATDYKPIATIDVKRNIFDLCTDTKDCYLAVIENQGSMDTVCRLYEVG
3D structure
PDB9bhs Crystal structure of the WDR domain of human DCAF1 in complex with OICR-9939 compound
ChainB
Resolution1.43 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1APJ B T1139 H1140 Y1181 R1225 C1227 R1298 V1299 A1311 P1329 F1330 F1355 D1356 L1357 T61 H62 Y103 R147 C149 R220 V221 A233 P241 F242 F267 D268 L269
Gene Ontology
Biological Process
GO:0016567 protein ubiquitination

View graph for
Biological Process
External links
PDB RCSB:9bhs, PDBe:9bhs, PDBj:9bhs
PDBsum9bhs
PubMed
UniProtQ9Y4B6|DCAF1_HUMAN DDB1- and CUL4-associated factor 1 (Gene Name=DCAF1)

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