Structure of PDB 9b6j Chain B

Receptor sequence
>9b6jB (length=896) Species: 10090 (Mus musculus) [Search protein sequence]
DLVNFIQANFKDAFGDIQFGKYLRLSCDTDSETLYELLTQHWHLKTPNLV
ISVTGGAKNFALKPRMRKIFSRLIYIAQSKGAWILTGGTHYGLMKYIGEV
VRDNTISENIVAIGIAAWGMVSNRDTLFSAQYIMLYILDNNHTHLLLVDN
GCHGHPTVEAKLRNQLEKYISERTSQDSNYGGKIPIVCFAQGGGRETLKA
INTSVKSKIPCVVVEGSGQIADVIASLVTSSMVKEKLVRFLPRTVSRLPE
EEIESWIKWLKEILESSHLLTVIKMEEAGDEIVSNAISYALYKAFSTNEQ
DKDNWNGQLKLLLEWNQLDLASDEIFTNDRRWESADLQEVMFTALIKDRP
KFVRLFLENGLNLQKFLTNEVLTELFSTHFSTLVYRNLQIAKNSYNDALL
TFVWKLVANFRRSTRHPLQALFIWAILQNKKELSKVIWEQTKGCTLAALG
ASKLLKTLAKVKNDINAAGESEELANEYETRAVELFTECYSNDEDLAEQL
LVYSCEAWGGSNCLELAVEATDQHFIAQPGVQNFLSKQWYGEISRDTKNW
KIILCLFIIPLVGCGLVKKLLWYYVAFFTSPFVVFSWNVVFYIAFLLLFA
YVLLMDFHSVPHTPELILYALVFVLFCDEVRQWYMNGVNYFTDLWNVMDT
LGLFYFIAGIVFRLHSSNKSSLYSGRVIFCLDYIIFTLRLIHIFTVSRNL
GPKIIMLQRMLIDVFFFLFLFAVWMVAFGVARQGILRQNEQRWRWIFRSV
IYEPYLAMFGQVPSDVDSTTYLVCIYMLSTNILLVNLLVAMFGYTVGIVQ
ENNDQVWKFQRYFLVQEYCNRLNIPFPFVVFAYFYMVVKKCNETLAWEGV
MKENYLVKINTKANDNSEEMRHRFRQLDSKLNDLKSLLKEIANNIK
3D structure
PDB9b6j Mechanisms of sensory adaptation and inhibition of the cold and menthol receptor TRPM8.
ChainB
Resolution3.53 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B E782 Q785 E629 Q632
BS02 PIO B R688 N692 S739 F847 S850 R851 R545 N549 S586 F694 S697 R698
External links
PDB RCSB:9b6j, PDBe:9b6j, PDBj:9b6j
PDBsum9b6j
PubMed39093967
UniProtQ8R4D5|TRPM8_MOUSE Transient receptor potential cation channel subfamily M member 8 (Gene Name=Trpm8)

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