Structure of PDB 9b6i Chain B

Receptor sequence
>9b6iB (length=856) Species: 9157 (Parus major) [Search protein sequence]
GDIQFGKYIRLSCETLYDLMTQHWHLKTPNLVISVTGGAKNFALKPRMRK
IFSRLIYIAQSKGAWIFTGGTHYGLMKYIGEVVRDNTISENVVAIGIAAW
GMISNRETDGSFLLYCLDNNHTHLLLVDAKVRTQLEKYISERVIPESNYG
GKIPIVCFAQGGGKETLKSINVAIKSKIPCVVVEGSGRIADVIASLVASS
CVKESLLRFLPRTISRLSEEETESWIKWIKEVLESPHLLTVIKIEEAGDE
IVSNAISFALYKAFSTNEHDRDNWNGQLKLLLEWNQLDLASDEIFTNDRN
WESADLQDVMFTALVKDRPKFVRLFLENGLNLRKFLTTEVLRELYTNNFS
SLVFKNLQIAKNSYNDALLTFVWKMVEDFRRGRHPLQALFIWSVLQNKKE
LSKVIWEQTRGCTLAALGASKLLKSMAKVKNDINAAGESEELANEYETRA
VELFTECYSNDEDLAEQLLTYSCEAWGGSNCLELAVEARDQQFIAQPGVQ
NFLSKQWYGEISRDTKNWKIIMCLLYYVSFFTSPFVVFSWNVIFYIAFLL
LFAYVLLMDFQKEPTALEIILYVLVFVLLCDEWYMNGSKYFSDLWNVMDT
LAIFYFIAGIVFRLHSDESSWYSGRVIFCLDYIVFTLRLIHIFTVSRNLG
PKIIMLQRMMIDVFFFLFLFAVWMVAFGVARQGILRKNEHRWEWIFRSVI
YEPYLAMFGQYPDDIDGTTYNFDRCTFSGNESKPLCVELDANNQPRFPEW
ITIPLVCIYMLSTNILLVNLLVAMFGYTVGSVQENNDQVWKFQRFFLVQE
YNEILAWEAVMKENYLVKINTKANDSSEEMVHRFRQLDAKLSDLKGLLKE
ISSKIK
3D structure
PDB9b6i Mechanisms of sensory adaptation and inhibition of the cold and menthol receptor TRPM8.
ChainB
Resolution3.26 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 Y01 B I961 P964 I751 P754
BS02 T14 B W883 L965 S972 W673 L755 S762
BS03 Y01 B F853 S856 F643 S646
BS04 Y01 B W692 S749 I753 V855 W507 S539 I543 V645
BS05 Y01 B L804 W805 L594 W595
BS06 T14 B L866 M869 L656 M659
BS07 Y01 B M884 I910 Y914 M674 I700 Y704
External links