Structure of PDB 9b6d Chain B

Receptor sequence
>9b6dB (length=933) Species: 10090 (Mus musculus) [Search protein sequence]
DLVNFIQANFKDAFGDIQFGKYLRLSCDTDSETLYELLTQHWHLKTPNLV
ISVTGGAKNFALKPRMRKIFSRLIYIAQSKGAWILTGGTHYGLMKYIGEV
VRDNTISENIVAIGIAAWGMVSNRDTLFSAQYIMLYILDNNHTHLLLVDN
GCHGHPTVEAKLRNQLEKYISERTSQDSNYGGKIPIVCFAQGGGRETLKA
INTSVKSKIPCVVVEGSGQIADVIASLVTSSMVKEKLVRFLPRTVSRLPE
EEIESWIKWLKEILESSHLLTVIKMEEAGDEIVSNAISYALYKAFSTNEQ
DKDNWNGQLKLLLEWNQLDLASDEIFTNDRRWESADLQEVMFTALIKDRP
KFVRLFLENGLNLQKFLTNEVLTELFSTHFSTLVYRNLQIAKNSYNDALL
TFVWKLVANFRRTRHPLQALFIWAILQNKKELSKVIWEQTKGCTLAALGA
SKLLKTLAKVKNDINAAGESEELANEYETRAVELFTECYSNDEDLAEQLL
VYSCEAWGGSNCLELAVEATDQHFIAQPGVQNFLSKQWYGEISRDTKNWK
IILCLFIIPLVGCGLVSFRKKKKLLWYYVAFFTSPFVVFSWNVVFYIAFL
LLFAYVLLMDFHSVPHTPELILYALVFVLFCDEVRQWYMNGVNYFTDLWN
VMDTLGLFYFIAGIVFRLHSSNKSSLYSGRVIFCLDYIIFTLRLIHIFTV
SRNLGPKIIMLQRMLIDVFFFLFLFAVWMVAFGVARQGILRQNEQRWRWI
FRSVIYEPYLAMFGQVPSDVDSTTYDFSHCTFSGNESKPLCVELDEHNLP
RFPEWITIPLVCIYMLSTNILLVNLLVAMFGYTVGIVQENNDQVWKFQRY
FLVQEYCNRLNIPFPFVVFAYFYMVVKKNETLAWEGVMKENYLVKINTKA
NDNSEEMRHRFRQLDSKLNDLKSLLKEIANNIK
3D structure
PDB9b6d Mechanisms of sensory adaptation and inhibition of the cold and menthol receptor TRPM8.
ChainB
Resolution3.3 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 Y01 B L750 S850 L601 S701
BS02 Y01 B F735 R851 F586 R702
External links
PDB RCSB:9b6d, PDBe:9b6d, PDBj:9b6d
PDBsum9b6d
PubMed39093967
UniProtQ8R4D5|TRPM8_MOUSE Transient receptor potential cation channel subfamily M member 8 (Gene Name=Trpm8)

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