Structure of PDB 9asj Chain B

Receptor sequence
>9asjB (length=741) Species: 9606 (Homo sapiens) [Search protein sequence]
KLLLANWGLPKAVLEKYHSFGVKKMFEWQAECLLLGQVLEGKNLVYSAPT
SAGKTLVAELLILKRVLEMRKKALFILPFVSVAKEKKYYLQSLFQEVGIK
VDGYMGSTSPSRHFSSLDIAVCTIERANGLINRLIEENKMDLLGMVVVDE
LHMLGDSHRGYLLELLLTKICYITRKSASSNAVQIVGMSATLPNLELVAS
WLNAELYHTDFRPVPLLESVKVGNSIYDSSMKLVREFEPMLQVEDHVVSL
CYETICDNHSVLLFCPSKKWCEKLADIIAREFYNLHHQAEQKELLEVMDQ
LRRLPSGLDSVLQKTVPWGVAFHHAGLTFEERDIIEGAFRQGLIRVLAAT
STLSSGVNLPARRVIIRTPIFGGRPLDILTYKQMVGRAGRKGVDTVGESI
LICKNSEKSKGIALLQGSLKPVRSCLVTGSMIRAILEIIVGGVASTSQDM
HTYAACTFLAASMGAIEACVMWLLENEFIQSTEKVYHPTHLGSATLSSSL
SPADTLDIFADLQRAMKGFVLENDLHILYLVTPMFEDWTTIDWYRFFCLW
EKLPTSMKRVAELVGVEEGFLARCVKGKQHRQMAIHKRFFTSLVLLDLIS
EVPLREINQKYGCNRGQIQSLQQSAAVYAGMITVFSNRLGWHNMELLLSQ
FQKRLTFGIQRELCDLVRVSLLNAQRARVLYASGFHTVADLARANIVEVE
VILKNAVPMRTIWVTGRKGLTEREAAALIVEEARMILQQDL
3D structure
PDB9asj Structural Basis for Pol theta-Helicase DNA Binding and Microhomology-Mediated End-Joining.
ChainB
Resolution3.5 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ANP B V89 K91 F93 Q96 T117 S118 G120 K121 T122 L123 K153 N451 V22 K24 F26 Q29 T50 S51 G53 K54 T55 L56 K86 N358
External links
PDB RCSB:9asj, PDBe:9asj, PDBj:9asj
PDBsum9asj
PubMed38895274
UniProtO75417|DPOLQ_HUMAN DNA polymerase theta (Gene Name=POLQ)

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