Structure of PDB 8yrs Chain B

Receptor sequence
>8yrsB (length=530) Species: 9606 (Homo sapiens) [Search protein sequence]
SSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLV
MPTGGGKSLCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLN
ASSSKEHVKWVHAEMVNKNSELKLIYVTPEKIAKSKMFMSRLEKAYEARR
FTRIAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASLIGLTATATNHVL
TDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDFIEDIVKLINGRY
KGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSA
NEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKA
DCILYYGFGDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHF
DEVWNSEACNKMCDNCCKGSAFERKNITEYCRDLIKILKQAEELNEKLTP
LKLIDSWMGKGAAKLRVAGVVAPTLPREDLEKIIAHFLIQQYLKEDYSFT
AYATISYLKIGPKANLLNNEAHAITMQVTK
3D structure
PDB8yrs Crystal structure of human RECQ1 helicase containing a flexible linker in complex with tailed duplex DNA
ChainB
Resolution2.43 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B T521 Y574 Y579 T449 Y502 Y507
BS02 dna B Q324 K325 A346 V372 A373 M429 Y574 T576 Q262 K263 A284 V310 A311 M367 Y502 T504
BS03 ZN B C453 C471 C475 C478 C391 C409 C413 C416
External links
PDB RCSB:8yrs, PDBe:8yrs, PDBj:8yrs
PDBsum8yrs
PubMed
UniProtP46063|RECQ1_HUMAN ATP-dependent DNA helicase Q1 (Gene Name=RECQL)

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