Structure of PDB 8yr3 Chain B

Receptor sequence

>8yr3B (length=587) Species: 9606 (Homo sapiens) [Search protein sequence]

RDFGRKLRLLSGYLWPRGSPALQLVVLICLGLMGLERALNVLVPIFYRNI
VNLLTEKAPWNSLAWTVTSYVFLKFLQGGGTGSTGFVSNLRTFLWIRVQQ
FTSRRVELLIFSHLHELSLRWHLGRRTGEVLRIADRGTSSVTGLLSYLVF
NVIPTLADIIIGIIYFSMFFNAWFGLIVFLCMSLYLTLTIVVTEWRTKFR
RAMNTQENATRARAVDSLLNFETVKYYNAESYEVERYREAIIKYQGLEWK
SSASLVLLNQTQNLVIGLGLLAGSLLCAYFVTEQKLQVGDYVLFGTYIIQ
LYMPLNWFGTYYRMIQTNFIDMENMFDLLKEETEVKDLPGAGPLRFQKGR
IEFENVHFSYADGRETLQDVSFTVMPGQTLALVGPSGAGKSTILRLLFRF
YDISSGCIRIDGQDISQVTQASLRSHIGVVPQDTVLFNDTIADNIRYGRV
TAGNDEVEAAAQAAGIHDAIMAFPEGYRTQVGERGLKLSGGEKQRVAIAR
TILKAPGIILLDEATSALDTSNERAIQASLAKVCANRTTIVVAHRLSTVV
NADQILVIKDGCIVERGRHEALLSRGGVYADMWQLQQ

3D structure

PDB

8yr3 Cryo-EM structure of cadmium-bound human ABCB6.

Chain

Resolution

3.2 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	GSH	B	N498 N545 W546 G548 T549	N259 N306 W307 G309 T310

External links

PDB	RCSB:8yr3, PDBe:8yr3, PDBj:8yr3
PDBsum	8yr3
PubMed	38822018
UniProt	Q9NP58\|ABCB6_HUMAN ATP-binding cassette sub-family B member 6 (Gene Name=ABCB6)

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