Structure of PDB 8xr4 Chain B

Receptor sequence
>8xr4B (length=331) Species: 1038928 (Streptomyces xinghaiensis) [Search protein sequence]
MEYTQLGRIGLKVSRLVLGTMNFGPTTDEAESHAIMDAALDAGINFFDTA
NVYGWGENKGRTEEILGSWFAQGGDRRDKVVLATKVYGNMGLDGPAWPNH
DKLSALNIRRSVDASLKRLGTDHIDLYQFHHVDRDTPWDEIWQAMDVLVR
QGKILYVGSSNFAGWNIAQANETAARHGRLGLVSEQCLYNLCERRAEMEV
VPAAREYGLGVIAWSPLHGGLLGGAIRKEQEGGNRRAASGRAADALKDPQ
QREQIQRYEDLLDKHGLEPGEVALAWLLTRPGVTGPIVGPRTADQLASAV
RAAELTLTDEVLTALDEIFPGPGPSPEAFAW
3D structure
PDB8xr4 A three-level regulatory mechanism of the aldo-keto reductase subfamily AKR12D
ChainB
Resolution1.94 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP B G19 M21 D48 Y53 N161 Q186 W214 S215 P216 L217 G219 G220 R235 R236 A237 I287 G289 R291 Q295 S298 G19 M21 D48 Y53 N161 Q186 W214 S215 P216 L217 G219 G220 R235 R236 A237 I287 G289 R291 Q295 S298
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Cellular Component
External links
PDB RCSB:8xr4, PDBe:8xr4, PDBj:8xr4
PDBsum8xr4
PubMed38459030
UniProtA0A3R7J519

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