Structure of PDB 8xpn Chain B

Receptor sequence
>8xpnB (length=347) Species: 9606 (Homo sapiens) [Search protein sequence]
IRNLNPVFGGSGPALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQ
DDINRSNLLGHKGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQF
AGYSQQDSQELLLFLMDGLHEDLNKADNRKRYENNDHLDDFKAAEHAWQK
HKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKCT
LQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKR
FSYDGRWKQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGL
DGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYILFYTSLG
3D structure
PDB8xpn The Crystal Structure of USP8 from Biortus.
ChainB
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.19.12: ubiquitinyl hydrolase 1.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C936 C939 C985 C988 C173 C176 C222 C225
Gene Ontology
Molecular Function
GO:0004843 cysteine-type deubiquitinase activity
Biological Process
GO:0016579 protein deubiquitination

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Molecular Function
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Biological Process
External links
PDB RCSB:8xpn, PDBe:8xpn, PDBj:8xpn
PDBsum8xpn
PubMed
UniProtP40818|UBP8_HUMAN Ubiquitin carboxyl-terminal hydrolase 8 (Gene Name=USP8)

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