Structure of PDB 8x91 Chain B

Receptor sequence
>8x91B (length=964) Species: 9606 (Homo sapiens) [Search protein sequence]
PFPSAVTIKSWVDKMQEDLVTLAKTASGVNQLVDIYEKYQDLYTVEPNNA
RQLVEIAARDIEKLLSNRSKALVRLALEAEKVQAAHQWREDFASNEVVYY
NAKDDLDPEKEPGSQRIKPVFIEDANFGRQISYQHAAVHIPTDIYEGSTI
VLNELNWTSALDEVFKKNREEDPSLLWQVFGSATGLARYYPASPWVDNKI
DLYDVRRRPWYIQGAASPKDMLILVDVSGSVSGLTLKLIRTSVSEMLETL
SDDDFVNVASFNSNAQDVSCFQHLVQANVRNKKVLKDAVNNITAKGITDY
KKGFSFAFEQLLNYNVSRANCNKIIMLFTDGGEERAQEIFNKYNKDKKVR
VFTFSVGQHNYDRGPIQWMACENKGYYYEIPSIGAIRINTQEYLDVLGRP
MVLAGDKAKQVQWTNVYLDALELGLVITGTLPVFNITGQFENKTNLKNQL
ILGVMGVDVSLEDIKRLTPRFTLCPNGYYFAIDPNGYVLLHPNLQPKPIG
VGIPTINSQEPVTLDFLDAELENDIKVEIRNKMIDGESGEKTFRTLVKSQ
DERYIDKGNRTYTWTPVNGTDYSLALVLPTYSFYYIKAKLEETITQARYS
ETLKPDNFEESGYTFIAPRDYCNDLKISDNNTEFLLNFNEFIDRKTPNNP
SCNADLINRVLLDAGFTNELVQNYWSKQKNIKGVKARFVVTDGGITRVYP
KEAGENWQENPETYEDSFYKRSLDNDNYVFTAPYFNKSGPGAYESGIMVS
KAVEIYIQGKLLKPAVVGIKIDVNSWIENFTKTSIRDPCAGPVCDCKRNS
DVMDCVILDDGGFLLMANHDDYTNQIGRFFGEIDPSLMRHLVNISVYAFN
KSYDYQSVCEPCITEQTQYFFDNDSKSFSGVLDCGNCSRIFHGEKLMNTN
LIFIMVESKGTCPCDTRLLIQAEQTSDGPNPCDMVKQPRYRKGPDVCFDN
NVLEDYTDCGGVSG
3D structure
PDB8x91 Structural basis for different omega-agatoxin IVA sensitivities of the P-type and Q-type Ca v 2.1 channels.
ChainB
Resolution3.11 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B S261 S263 T331 S228 S230 T298
External links
PDB RCSB:8x91, PDBe:8x91, PDBj:8x91
PDBsum8x91
PubMed38443561
UniProtP54289|CA2D1_HUMAN Voltage-dependent calcium channel subunit alpha-2/delta-1 (Gene Name=CACNA2D1)

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