Structure of PDB 8x5f Chain B

Receptor sequence
>8x5fB (length=616) Species: 9606 (Homo sapiens) [Search protein sequence]
MKFAEHLSAHITPEWRKQYIQYEAFKDMLYSAQDQAPSVEVTDEDTVKRY
FAKFEEKFFQTCEKELAKINTFYSEKLAEAQRRFATLQNELQSSLDAQKE
STGSHEERVQHRNIKDLKLAFSEFYLSLILLQNYQNLNFTGFRKILKKHD
KILETSRGADWRVAHVEVAPFYTCKKINQLISETEAVVTNELEDGDRQKA
MKRLRVPPLGAAQPAPAWTTFRVGLFCGIFIVLNITLVLAAVFKLETDRS
IWPLIRIYRGGFLLIEFLFLLGINTYGWRQAGVNHVLIFELNPRSNLSHQ
HLFEIAGFLGILWCLSLLACFFAPISVIPTYVYPLALYGFMVFFLINPTK
TFYYKSRFWLLKLLFRVFTAPFHKVGFADFWLADQLNSLSVILMDLEYMI
CFYSLELKWDESKGLLPSGICHKYTYGVRAIVQCIPAWLRFIQCLRRYRD
TKRAFPHLVNAGKYSTTFFMVTFAALYSTHKERGHSDTMVFFYLWIVFYI
ISSCYTLIWDLKMDWGLFDKNAGENTFLREEIVYPQKAYYYCAIIEDVIL
RFAWTIQISITSTTLLPHSGDIIATVFAPLEVFRRFVWNFFRLENEHLNN
CGEFRAVRDISVAPLN
3D structure
PDB8x5f structure of transport at 2.9 Angstroms resolution
ChainB
Resolution2.96 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PO4 B N401 R570 W573 N387 R551 W554
BS02 PO4 B W528 M532 R611 W509 M513 R592
BS03 PO4 B F394 R459 C463 R466 F380 R440 C444 R447
BS04 PO4 B R270 R273 M408 R256 R259 M394
BS05 IHP B M1 K2 K158 K161 K165 M1 K2 K144 K147 K151
Gene Ontology
Molecular Function
GO:0000822 inositol hexakisphosphate binding
GO:0001618 virus receptor activity
GO:0005315 phosphate transmembrane transporter activity
GO:0015562 efflux transmembrane transporter activity
Biological Process
GO:0006817 phosphate ion transport
GO:0009615 response to virus
GO:0016036 cellular response to phosphate starvation
GO:0030643 intracellular phosphate ion homeostasis
GO:0035435 phosphate ion transmembrane transport
GO:0046718 symbiont entry into host cell
Cellular Component
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8x5f, PDBe:8x5f, PDBj:8x5f
PDBsum8x5f
PubMed39169184
UniProtQ9UBH6|S53A1_HUMAN Solute carrier family 53 member 1 (Gene Name=XPR1)

[Back to BioLiP]