Structure of PDB 8wwo Chain B

Receptor sequence
>8wwoB (length=398) Species: 10497 (African swine fever virus) [Search protein sequence]
MEAFEISDFKEHAKKKSMWAGALNKVTISGLMGVFTEDEDLMALPIHRDH
CPALLKIFDEIIVNATDHERACHNKTKKVTYIKISFDKGVFSCENDGPGI
PIAKHEQASLIAKRDVYVPEVASCHFLAGTNINKAKDCIKGGTNGVGLKL
AMVHSQWAILTTADGAQKYVQHINQRLDIIEPPTITPSREMFTRIELMPV
YQELGYAEPLSETEQADLSAWIYLRACQCAAYVGKGTTIYYNDKPCRTGS
VMALAKMYTLLSAPNSTIHTATIKADAKPYSLHPLQVAAVVSPKFKKFEH
VSVINGVNCVKGEHVTFLKKTINEMVVKKFQQTIKTTLRDSCSNIFIVIV
GSIPGIEWTGQRKDELSIAENVFKTHYSIPSSFLTSMTKSIVDILLQS
3D structure
PDB8wwo Crystal of the AFSV topoisomerase ATPase domain in complex with AMPPNP
ChainB
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.6.2.2: DNA topoisomerase (ATP-hydrolyzing).
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ANP B N64 H68 I100 A122 T130 G142 T143 N144 G145 V146 G147 L148 K149 N64 H68 I100 A122 T130 G142 T143 N144 G145 V146 G147 L148 K149
External links