Structure of PDB 8wov Chain B

Receptor sequence

>8wovB (length=341) Species: 3702 (Arabidopsis thaliana)

MAKSVLVTGGAGYIGSHTVLQLLEGGYSAVVVDNYDNSSAASLQRVKKLA
GENGNRLSFHQVDLRDRPALEKIFSETKFDAVIHFAGLKAVGESVEKPLL
YYNNNIVGTVTLLEVMAQYGCKNLVFSSSATVYGWPKEVPCTEESPISAT
NPYGRTKLFIEEICRDVHRSDSEWKIILLRYFNPVGAHPSGYIGEDPLGV
PNNLMPYVQQVAVGRRPHLTVFGTDYKTKDGTAVRDYIHVMDLADGHIAA
LRKLDDLKISCEVYNLGTGNGTSVLEMVAAFEKASGKKIPLVMAGRRPGD
AEVVYASTEKAERELNWKAKNGIEEMCRDLWNWASNNPYGY

3D structure

• PDB: 8wov Cytosolic UDP-L-arabinose synthesis by bifunctional UDP-glucose 4-epimerases in Arabidopsis.
• Chain: B
• Resolution: 2.25 Å

Enzymatic activity

• Enzyme Commision number: 5.1.3.2: UDP-glucose 4-epimerase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	NAD	B	G9 G12 Y13 I14 D33 N34 D36 N37 S38 D63 L64 F85 A86 G87 K89 N104 S127 S129 Y153 K157 Y181 P184	G9 G12 Y13 I14 D33 N34 D36 N37 S38 D63 L64 F85 A86 G87 K89 N104 S127 S129 Y153 K157 Y181 P184
BS02	UDP	B	N183 N203 L204 L219 T220 F222 R235 Y237 R297 D300	N183 N203 L204 L219 T220 F222 R235 Y237 R297 D300

Gene Ontology

Molecular Function

• GO:0003978 UDP-glucose 4-epimerase activity
• GO:0016853 isomerase activity
• GO:1901149 salicylic acid binding

Biological Process

• GO:0006012 galactose metabolic process
• GO:0042546 cell wall biogenesis
• GO:0071555 cell wall organization

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol

External links

• PDB: RCSB:8wov, PDBe:8wov, PDBj:8wov
• PDBsum: 8wov
• PubMed: 38678521
• UniProt: Q9T0A7|UGE2_ARATH UDP-glucose 4-epimerase 2 (Gene Name=UGE2)