Structure of PDB 8w8g Chain B

Receptor sequence
>8w8gB (length=206) Species: 9606 (Homo sapiens) [Search protein sequence]
EDAGLVAEAEAVAAGWMLDFLCLSLCRAFRDGRSEDFRRTRNSAEAIIHG
LSSLTACQLRTIYICQFLTRIAAGKTLDAQFENDERITPLESALMIWGSI
EKEHDKLHEEIQNLIKIQAIAVCMENGNFKEAEEVFERIFGDPNSHMPFK
SKLLMIISQKDTFHSFFQHFSYNHMMEKIKSYVNYVLSEKSSTFLMKAAA
KVVESK
3D structure
PDB8w8g PinX1 suppress tumorigenesis through inhibiting telomerase activity
ChainB
Resolution2.7 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B R102 E106 I109 H110 S113 I123 Q127 R131 D139 A140 Q141 F142 E146 R147 E192 R41 E45 I48 H49 S52 I62 Q66 R70 D78 A79 Q80 F81 E85 R86 E131
External links
PDB RCSB:8w8g, PDBe:8w8g, PDBj:8w8g
PDBsum8w8g
PubMed
UniProtP54274|TERF1_HUMAN Telomeric repeat-binding factor 1 (Gene Name=TERF1)

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