Structure of PDB 8w07 Chain B

Receptor sequence
>8w07B (length=229) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEEASMMGLLTNLADRELVHMINWAK
RVPGFVDLTSHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDR
NQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFL
SSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILS
HIRHMSNKGMEHLYKNVVPSYDLLLEMLD
3D structure
PDB8w07 Asymmetric allostery in estrogen receptor-alpha homodimers drives responses to the ensemble of estrogens in the hormonal milieu.
ChainB
Resolution1.83 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1AHZ B M343 T347 E353 W383 F404 I424 G521 L525 V533 M31 T35 E41 W71 F92 I112 G209 L213 V217
External links
PDB RCSB:8w07, PDBe:8w07, PDBj:8w07
PDBsum8w07
PubMed38830107
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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