Structure of PDB 8vy4 Chain B

Receptor sequence

>8vy4B (length=213) Species: 9606 (Homo sapiens) [Search protein sequence]

IDMTQTPSSKSVAVGDTVTINCQASETVYKNNYLAWYQQKPGQPPKRLIY
SVSTLDSGVPSRFSGSGSGTQFTLTISGVQCDDAATYYCAGYRTTPIYHI
RFGGGTEVVVEGDPVAPTVLIFPPAADQVATGTVTIVCVANKYFPDVTVT
WEVDGTTQTTGIENSKTPQNSADCTYNLSSTLTLTSTQYNSHKEYTCKVT
QGTTSVVQSFNRG

3D structure

PDB

8vy4 Engineering a tumor-selective prodrug T-cell engager bispecific antibody for safer immunotherapy.

Chain

Resolution

1.7 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	B	Y30 Y34 Y93 T95 T96 Y99	Y29 Y33 Y92 T94 T95 Y98

External links

PDB	RCSB:8vy4, PDBe:8vy4, PDBj:8vy4
PDBsum	8vy4
PubMed	38962811

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