Structure of PDB 8vq4 Chain B

Receptor sequence
>8vq4B (length=270) Species: 9606 (Homo sapiens) [Search protein sequence]
IAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRA
ILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSL
FIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTI
VSWLNVYMQVAYLQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALY
HFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADE
DAHNIQTHRDSLDLLDKARA
3D structure
PDB8vq4 Expanding the ligandable proteome by paralog hopping with covalent probes.
ChainB
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 A1AC5 B W95 Q240 Y243 H343 W14 Q159 Y162 H253
External links
PDB RCSB:8vq4, PDBe:8vq4, PDBj:8vq4
PDBsum8vq4
PubMed38293178
UniProtP24864|CCNE1_HUMAN G1/S-specific cyclin-E1 (Gene Name=CCNE1)

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