Structure of PDB 8vq3 Chain B

Receptor sequence
>8vq3B (length=270) Species: 9606 (Homo sapiens) [Search protein sequence]
IAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRA
ILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSL
FIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTI
VSWLNVYMQVAYLNYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALY
HFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADE
DAHNIQTHRDSLDLLDKARA
3D structure
PDB8vq3 Expanding the ligandable proteome by paralog hopping with covalent probes.
ChainB
Resolution1.84 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1AC4 B P91 W95 N236 Q240 Y243 F260 H343 P10 W14 N155 Q159 Y162 F170 H253
External links
PDB RCSB:8vq3, PDBe:8vq3, PDBj:8vq3
PDBsum8vq3
PubMed38293178
UniProtP24864|CCNE1_HUMAN G1/S-specific cyclin-E1 (Gene Name=CCNE1)

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