Structure of PDB 8vof Chain B

Receptor sequence
>8vofB (length=171) Species: 9606 (Homo sapiens) [Search protein sequence]
YDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDG
KTIKAQIWDTALERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKE
LRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFIETSALDS
TNVEAAFQTILTEIYRIVSQK
3D structure
PDB8vof Cryptosporidium PI(4)K inhibitor EDI048 is a gut-restricted parasiticidal agent to treat paediatric enteric cryptosporidiosis
ChainB
Resolution3.0 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP B G21 V22 G23 K24 S25 N26 F36 N37 L38 S40 N124 K125 D127 L128 S154 A155 L156 G14 V15 G16 K17 S18 N19 F29 N30 L31 S33 N116 K117 D119 L120 S146 A147 L148
External links
PDB RCSB:8vof, PDBe:8vof, PDBj:8vof
PDBsum8vof
PubMed
UniProtP62491|RB11A_HUMAN Ras-related protein Rab-11A (Gene Name=RAB11A)

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