Structure of PDB 8var Chain B

Receptor sequence
>8varB (length=362) Species: 562 (Escherichia coli) [Search protein sequence]
MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVG
KTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEIDAASRTK
VEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHV
KFLLATTDPQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEP
RALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAMLGTLDDDQAL
SLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPA
ALGNDMAAIELRMRELARTIPPTDIQLYYQTLLIGRKELPYAPDRRMGVE
MTLLRALAFHPR
3D structure
PDB8var Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication.
ChainB
Resolution3.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B T99 K100 V101 S132 H134 T99 K100 V101 S132 H134
BS02 ZN B C64 C76 C79 C64 C76 C79
BS03 ADP B A7 R11 P12 D17 V18 V19 G48 V49 G50 K51 T52 S53 L214 A7 R11 P12 D17 V18 V19 G48 V49 G50 K51 T52 S53 L214
BS04 BEF B G48 K51 R215 G48 K51 R215
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006260 DNA replication
Cellular Component
GO:0009360 DNA polymerase III complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8var, PDBe:8var, PDBj:8var
PDBsum8var
PubMed38490435
UniProtP06710|DPO3X_ECOLI DNA polymerase III subunit tau (Gene Name=dnaX)

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