Structure of PDB 8v9g Chain B

Receptor sequence
>8v9gB (length=266) Species: 573 (Klebsiella pneumoniae) [Search protein sequence]
SEKLTFKTDLEKLEREKAAQIGVAIVDPQGEIVAGHRMAQRFAMCSTFKF
PLAALVFERIDSGTERGDRKLSYGPDMIVEWSPATERFLASGHMTVLEAA
QAAVQLSDNGATNLLLREIGGPAAMTQYFRKIGDSVSRLDRKEPEMSDNT
PGDLRDTTTPIAMARTVAKVLYGGALTSTSTHTIERWLIGNQTGDATLRA
GFPKDWVVGEKTGTCANGGRNDIGFFKAQERDYAVAVYTTAPKLSAVERD
ELVASVGQVITQLILS
3D structure
PDB8v9g Restricted Rotational Flexibility of the C5 alpha-Methyl-Substituted Carbapenem NA-1-157 Leads to Potent Inhibition of the GES-5 Carbapenemase.
ChainB
Resolution1.62 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.2.6: beta-lactamase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MER B C63 S64 W99 S125 N127 E161 S165 T230 G231 T232 C45 S46 W81 S107 N109 E143 S147 T212 G213 T214
Gene Ontology
Molecular Function
GO:0008800 beta-lactamase activity
Biological Process
GO:0017001 antibiotic catabolic process
GO:0030655 beta-lactam antibiotic catabolic process
GO:0046677 response to antibiotic

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Molecular Function
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Biological Process
External links
PDB RCSB:8v9g, PDBe:8v9g, PDBj:8v9g
PDBsum8v9g
PubMed38511828
UniProtQ09HD0|BLAG5_KLEPN Beta-lactamase GES-5 (Gene Name=blaGES-5)

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