Structure of PDB 8v4o Chain B

Receptor sequence
>8v4oB (length=628) Species: 5476 (Candida albicans) [Search protein sequence]
THNVVHEANGVKLRETPKEFFERQPNKGHIHDVNQYKQMYEQSIKDPQGF
FGPLAKELLSWDHDFHTVKSGTLKNGDAAWFLGGELNASYNCVDRHAFAN
PDKPALICEADDEKDSHILTYGDLLREVSKVAGVLQSWGIKKGDTVAVYL
PMNAQAIIAMLAIARLGAAHSVIFAGFSAGSIKDRVNDASCKALITCDEG
KRGGRTTNIKKLCDEALVDCPTVEKVLVYKRTNNPEIHLTEGRDYYWDVE
TAKFPGYLPPVSVNSEDPLFLLYTTPKGVVHSTAGYLLGAALSTKYIFDI
HPEDILFTAGDVGWITGHTYALYGPLLLGVPTIIFEGTPAYPDYGRFWQI
VEKHKATHFYVAPTALRLLRKAGEQEIAKYDLSSLRTLGSVGEPISPDIW
EWYNEFVGKNQCHISDTYWQTESGSHLIAPLAGVVPNKPGSASYPFFGID
AALIDPVTGVEIEGNDAEGVLAIKDHWPSMARTVYKNHTKYMDTYMNPYP
GYYFTGDGAARDHDGYYWIRGRVDDVVNVSGHRLSTAEIEAALIEDKKVS
EAAVVGIHDDITGQAVIAYVALGLRKELVLQVRKTIGPFAAPKSVIIVQD
IMRRILRKVSSNLSNPQSVEGIISAFGA
3D structure
PDB8v4o Crystal structure of Acetyl-CoA synthetase 2 in complex with AMP from Candida albicans
ChainB
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.2.1.1: acetate--CoA ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP B I340 G417 E418 P419 T442 Y443 W444 Q445 D532 I315 G392 E393 P394 T417 Y418 W419 Q420 D507
Gene Ontology
Molecular Function
GO:0003987 acetate-CoA ligase activity
GO:0005524 ATP binding
GO:0016208 AMP binding
GO:0016874 ligase activity
Biological Process
GO:0019427 acetyl-CoA biosynthetic process from acetate

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Molecular Function
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Biological Process
External links
PDB RCSB:8v4o, PDBe:8v4o, PDBj:8v4o
PDBsum8v4o
PubMed
UniProtQ8NJN3|ACS2_CANAL Acetyl-coenzyme A synthetase 2 (Gene Name=ACS2)

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