Structure of PDB 8v1t Chain B

Receptor sequence

>8v1tB (length=265) Species: 10306 (Human alphaherpesvirus 1 strain KOS) [Search protein sequence]

GAPCQVVLQGAELNGILQAFAPLRTSLLDSLLVMGDRGILIHNTIFGEQV
FLPLEHSQFSRYRWRGPTAAFLSLVDQKRSLLSVFRANQYPDLRRVELAI
TGQAPFRTLVQRIWTTTSDGEAVELASETLMKRELTSFVVLVPQGTPDVQ
LRLTRPQLTKVLNATGADSATPTTFELGVNGKFSVFTTSTCVTFAARENA
KTVYGENTHRTFSVVVDDCSMRAVLRRLQVAGGTLKFFLTTPVPSLCVTA
TGPNAVSAVFLLKPQ

3D structure

PDB

8v1t Viral DNA polymerase structures reveal mechanisms of antiviral drug resistance.

Chain

Resolution

2.8 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	B	K105 P183	K78 P156
BS02	dna	B	L50 R51 T52 R113 R279 R280	L23 R24 T25 R86 R226 R227

External links

PDB	RCSB:8v1t, PDBe:8v1t, PDBj:8v1t
PDBsum	8v1t
PubMed	39197451
UniProt	H9E949

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