Structure of PDB 8uyh Chain B

Receptor sequence
>8uyhB (length=370) Species: 121224 (Pediculus humanus corporis) [Search protein sequence]
DDELEGICWEIREAVSKVEQLQAANLDELDLGEPIAKGCNAVVYSAKLKH
QLAVKMMFNYDVESNSTAILKAMYRETVPAMSYFFIRLPPHPNIVRMYSV
FADRNMSLFLVMKRYDCTLKEYLRDKTPNMRSSILLLSQLLEAVAHMNIH
NISHRDLKSDNILVDLSEGDAYPTIVITDFGCCLCDKQNGLVIPYRSEDQ
DKGGNRALMAPEIANAKPGTFSWLNYKKSDLWAVGAIAYEIFNIDNPFYD
KKLLSKSYKEEDLPELPDTIPFIIRNLVSNMLSRSTNKRLDCDVAATVAQ
LYLWAPSSWLKENYTLPNSNEIIQWLLCLSSKVLCRRSLPEYELIASFLR
RVRLHLVRKGLKWIQELHIY
3D structure
PDB8uyh Interaction of PINK1 with nucleotides and kinetin.
ChainB
Resolution2.84 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ANP B A191 K193 M290 K291 Y293 L341 D357 A53 K55 M112 K113 Y115 L163 D179
BS02 MG B N339 D357 N161 D179
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8uyh, PDBe:8uyh, PDBj:8uyh
PDBsum8uyh
PubMed38241364
UniProtE0W1I1|PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial (Gene Name=Pink1)

[Back to BioLiP]