Structure of PDB 8utv Chain B

Receptor sequence
>8utvB (length=434) Species: 9823 (Sus scrofa) [Search protein sequence]
MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVY
YNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNN
WAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTL
LISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETY
CIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADL
RKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMM
AACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVK
TAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTG
EGMDEMEFTEAESNMNDLVSEYQQYQDATADEQG
3D structure
PDB8utv Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L
ChainB
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GDP B G10 Q11 C12 Q15 S138 T143 G144 D177 N204 Y222 N226 G10 Q11 C12 Q15 S138 T143 G144 D177 N204 Y222 N226
BS02 TA1 B D26 L215 H227 S234 R276 Q279 G360 D26 L215 H227 S234 R276 Q279 G360
Gene Ontology
Biological Process
GO:0007010 cytoskeleton organization
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005874 microtubule

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8utv, PDBe:8utv, PDBj:8utv
PDBsum8utv
PubMed38956021
UniProtA0A287AGU7

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