Structure of PDB 8utp Chain B

Receptor sequence
>8utpB (length=432) Species: 9823 (Sus scrofa) [Search protein sequence]
MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVY
YNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNN
WAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTL
LISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETY
CIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADL
RKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMM
AACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVK
TAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTG
EGMDEMEFTEAESNMNDLVSEYQQYQDATADE
3D structure
PDB8utp Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L
ChainB
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GDP B G10 Q11 C12 Q15 S138 G141 G142 T143 G144 D177 N204 Y222 N226 G10 Q11 C12 Q15 S138 G141 G142 T143 G144 D177 N204 Y222 N226
BS02 TA1 B E22 V23 D26 L215 H227 P272 L273 T274 R276 P358 R359 G360 L361 E22 V23 D26 L215 H227 P272 L273 T274 R276 P358 R359 G360 L361
Gene Ontology
Biological Process
GO:0007010 cytoskeleton organization
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005874 microtubule

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8utp, PDBe:8utp, PDBj:8utp
PDBsum8utp
PubMed38956021
UniProtA0A287AGU7

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