Structure of PDB 8uf5 Chain B

Receptor sequence
>8uf5B (length=831) Species: 1309 (Streptococcus mutans) [Search protein sequence]
VTTRLYKKYNQVYDRSAQSFEHVDHYLTAESWYRPKYILKDTWTTEKDFR
PLLMTWWPSQETQRQYVNYMNAQLGINKTYDDTSNQLQLNIAAATIQAKI
EAKITTLKNTDWLRQTISAFVKTQSAWNSDSEKPFDDHLQNGAVLYDNEG
KLTPYANSNYRILNRTPTNQTGKKDPRYTADNTIGGYEFLLANDVDNSNP
VVQAEQLNWLHFLMNFGNIYANDPDANFDSIRVDAVDNVDADLLQIAGDY
LKAAKGIHKNDKAANDHLSILEAWSDNDTPYLHDDGDNMINMDNKLRLSL
LFSLAKPLNQRSGMNPLITNSLVNRTDDNAETAAVPSYSFIRAHDSEVQD
LIRDIIKAEINPNVVGYSFTMEEIKKAFEIYNKDLLATEKKYTHYNTALS
YALLLTNKSSVPRVYYGDMFTDDGQYMAHKTINYEAIETLLKARIKYVSG
GQAMRNQQVGNSEIITSVRYGKGALKATDTGDRTTRTSGVAVIEGNNPSL
RLKASDRVVVNMGAAHKNQAYRPLLLTTDNGIKAYHSDQEAAGLVRYTND
RGELIFTAADIKGYANPQVSGYLGVWVPVGAAADQDVRVAASTAPSTDGK
SVHQNAALDSRVMFEGFSNFQAFATKKEEYTNVVIAKNVDKFAEWGVTDF
EMAPQYVSSTDGSFLDSVIQNGYAFTDRYDLGISKPNKYGTADDLVKAIK
ALHSKGIKVMADWVPDQMYAFPEKEVVTATRVDKFGKPVEGSQIKSVLYV
ADSKSSGKDQQAKYGGAFLEELQAKYPELFARKQISTGVPMDPSVKIKQW
SAKYFNGTNILGRGAGYVLKDQATNTYFNIS
3D structure
PDB8uf5 Structure-Based Discovery of Small Molecule Inhibitors of Cariogenic Virulence.
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.5: dextransucrase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B E405 D411 N455 D933 E188 D194 N238 D716
BS02 WIJ B D454 N455 N511 D237 N238 N294
Gene Ontology
Molecular Function
GO:0046527 glucosyltransferase activity
Biological Process
GO:0009250 glucan biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8uf5, PDBe:8uf5, PDBj:8uf5
PDBsum8uf5
PubMed28729722
UniProtP08987|GTFB_STRMU Glucosyltransferase-I (Gene Name=gtfB)

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