Structure of PDB 8u61 Chain B

Receptor sequence
>8u61B (length=700) Species: 9606 (Homo sapiens) [Search protein sequence]
RSWIQKVLEQIMDSPRQCVTPSEVVPVTVLAVQRYLLEDEPRDTVPKPPL
YCYDVTISDGVYQEKCYLDPSLNSLVYQNILKVGIQMRISRVSCLYNEKR
IGQGILCIDNVHCGETSDSISLETPFRNRAHQEKPERPLRGGKSHYLALW
NNEDPYGDIWLTDKQPEEHNFSDTKIISLSHLEMTWTNRRNFPALLVRIL
HKSKLRYYGKPDKKMIEPYQTFLEVADSSGTVSVIMWNALCPEWYKSLRV
GLVLLLQDYSVKKSYPFRIQPVPVDPQIKLISTMEICLNLRDPPTNIIII
PEKQVKPEWRLPKLNHRFTTRSELDDMPENCICDVIGLLVFVGRVQRSKK
KENREDFWSYRWIHIADGTSEQPFIVELFSTSQPEIFENIYPMAYFVCTQ
LKVVRNDNQVPKLLYLTTTNESGVFITGHRGQPYTYDAKVKNFIQWIRTK
SDSGEQKNMVIGGYYPYPPVPETFSKYSSSIKVESLLTAISEVRKEIEDL
QYREQKRIAIQGIITAIKYIPHSSISDRWESQLWREKKFGLIDHLHYSRV
YPESIPRKFMFEHRKFLSDQYNSQPAKYVPPEGRPPKLDDFKSARSLGHF
EVTILGLNHEIAIDVAFLPMYCPEDIRTSQIDTLLTSMNYSCAYPQDTTG
NDRLPGPRAVAGDIIKAATELDRVHIVGILDICNLGNNKVEVYLHKIYSP
3D structure
PDB8u61 Structure of RADX and mechanism for regulation of RAD51 nucleofilaments
ChainB
Resolution4.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B R232 R248 Y250 Q262 I277 W279 K304 Y307 N331 R333 E394 R190 R206 Y208 Q220 I235 W237 K262 Y265 N289 R291 E352
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003697 single-stranded DNA binding
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0006282 regulation of DNA repair
GO:2000042 negative regulation of double-strand break repair via homologous recombination
Cellular Component
GO:0005657 replication fork
GO:0005694 chromosome
GO:0016607 nuclear speck

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8u61, PDBe:8u61, PDBj:8u61
PDBsum8u61
PubMed38466836
UniProtQ6NSI4|RADX_HUMAN RPA-related protein RADX (Gene Name=RADX)

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