Structure of PDB 8u4d Chain B

Receptor sequence
>8u4dB (length=559) Species: 10116 (Rattus norvegicus) [Search protein sequence]
LDVARKTLKQFVNASYTDSYYKGQTALHIAIERRNMTLVTLLVENGADVQ
AAANGDFFKKTKGRPGFYFGELPLSLAACTNQLAIVKFLLQNSWQPADIS
ARDSVGNTVLHALVEVADNTVDNTKFVTSMYNEILILGAKLHPTLKLEEI
TNRKGLTPLALAASSGKIGVLAYILQREIHEPECRHLSRKFTEWAYGPVH
SSLYDLSCIDTCEKNSVLEVIAYSSSETPNRHDMLLVEPLNRLLQDKWDR
FVKRIFYFNFFVYCLYMIIFTAAAYYRPVEGLPPYKLKNTVGDYFRVTGE
ILSVSGGVYFFFRGIQYFLQRRPSLKSLFVDSYSEILFFVQSLFMLVSVV
LYFSQRKEYVASMVFSLAMGWTNMLYYTRGFQQMGIYAVMIEKMILRDLC
RFMFVYLVFLFGFSTAVVTLIEDGKYNSLYSTCLELFKFTIGMGDLEFTE
NYDFKAVFIILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQR
AITILDTEKSFRKAFRSGKLLQVGFTPDGKDDYRWCFRVDEVNWTTWNTN
VGIINEDPG
3D structure
PDB8u4d Structural basis of TRPV1 modulation by endogenous bioactive lipids.
ChainB
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 VPN B H410 Y511 S512 L515 F543 A546 M547 T550 R557 E570 Q700 H232 Y333 S334 L337 F365 A368 M369 T372 R379 E392 Q499
BS02 VPN B F591 L669 F413 L468
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8u4d, PDBe:8u4d, PDBj:8u4d
PDBsum8u4d
PubMed38698206
UniProtO35433|TRPV1_RAT Transient receptor potential cation channel subfamily V member 1 (Gene Name=Trpv1)

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