Structure of PDB 8u48 Chain B

Receptor sequence
>8u48B (length=264) Species: 226186 (Bacteroides thetaiotaomicron VPI-5482) [Search protein sequence]
TGIKNIVYIEVNDINPLNAGSYIMDDAPFFDYVILFAANIRGVGSDATLY
NNPNVQYILDHKDTLIKPLQDKGIKVLLGLLGDHTGLGFANMNSAQTEQF
ATAVANAVSQYGLDGVDFADAWAEYGRNGYPSGSTGSFSNLITALHNKMP
GKTITVFNYGYTSELTGVNSYIDYGIYAFFNSPSWSTGFGMPNSKFAPYT
INLNSAPSAASAQLYSGQVASKGYGAIGYYDLRANNIVSVLNGVAKGAFK
STCTYDGNSYPKNY
3D structure
PDB8u48 Human gut microbes express functionally distinct endoglycosidases to metabolize the same N-glycan substrate
ChainB
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 BMA B E52 W164 E10 W122
BS02 MAN B E52 D55 D273 E10 D13 D231
BS03 MAN B H126 W164 H84 W122
BS04 MAN B E52 N54 A79 N81 N94 E10 N12 A37 N39 N52
BS05 MAN B N54 N94 N12 N52
BS06 MAN B E166 R169 E124 R127
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:8u48, PDBe:8u48, PDBj:8u48
PDBsum8u48
PubMed38879612
UniProtQ8A889

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