Structure of PDB 8u1n Chain B

Receptor sequence
>8u1nB (length=497) Species: 7111 (Trichoplusia ni) [Search protein sequence]
TDSGEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRY
ESLTDPSKLDSGKELYIKIIPNKSEGTFTIIDTGIGMTKADLVNNLGTIA
KSGTKAFMEALQAGADISMIGQFGVGFYSCYLVADRVTVHSKHNDDEQYM
WESSAGGSFTVRTDHGEPLGRGTKIVLHIKEDLAEYLEVNKIKEIVKKHS
QFIGYPIKLTVEKEREKEKKKTIKEKYTEDEELNKTKPIWTRNADDITQE
EYGDFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENKKR
KNNIKLYVRRVFIMDNCEDLIPEYLNFIKGVVDSEDLPLNISREMLQQNK
ILKVIRKNLVKKCLELFEELAEDKENYKKYYEQFSKNLKLGIHEDAQNRT
KLADLLRYHTSASGDEACSLKEYVSRMKENQKHIYYITGENRDQVANSSF
VERVKKRGYEVVYMTEPIDEYVVQQMREYDGKTLVSVTKEGLELPED
3D structure
PDB8u1n Structural dynamics of RAF1-HSP90-CDC37 and HSP90 complexes reveal asymmetric client interactions and key structural elements.
ChainB
Resolution3.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP B N46 S47 A50 D88 M93 N101 G127 Q128 F129 G130 V131 G132 F133 T179 R391 N40 S41 A44 D82 M87 N95 G121 Q122 F123 G124 V125 G126 F127 T173 R343
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0051082 unfolded protein binding
GO:0097718 disordered domain specific binding
GO:0140662 ATP-dependent protein folding chaperone
Biological Process
GO:0006457 protein folding
GO:0034605 cellular response to heat
GO:0050821 protein stabilization
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0032991 protein-containing complex
GO:0048471 perinuclear region of cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8u1n, PDBe:8u1n, PDBj:8u1n
PDBsum8u1n
PubMed38431713
UniProtA0A7E5VSK5

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