Structure of PDB 8twg Chain B

Receptor sequence
>8twgB (length=385) Species: 1867846 (Legionella clemsonensis) [Search protein sequence]
KNIKILVVGAGIAGPAICYWLKRFGFSPVLIEKYASIRKGGQALDIRGIA
THLARVMGIYDQICDRRTRIECGRFVDSAGKVLHEEHGEKFGFRQDDEVE
ILRGDLVEILMKTIADVPCYFNKSIISMQQNADKVIVKFKDGKIENYDIV
IGADGIHSATRRMIFDKNEYQLIHLGSYLSTFTIPNYLGLSHTDLECEAN
HKLVSINSDNNPEIARAGFMFRSQHILKDIRDEHEQKQFLCDTFRDFGWE
TQNILNRMPESDDFYFDAITQVRMNSWTKGRIALIGDAGYCPSPLSGQGN
NLAFVGAYILAGELKTANANYMQAFSRYNALLRSFVDTNQEFGVWVSKSF
LVEDEVSKEIAEERSNRILAMIKLVSNAIILPQYE
3D structure
PDB8twg Sequence-structure-function characterization of the emerging tetracycline destructase family of antibiotic resistance enzymes.
ChainB
Resolution1.8 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD B V10 G11 A12 G13 I14 A15 E34 K35 R40 G43 Q44 R105 D156 G157 Y267 G288 D289 P296 G301 N302 V8 G9 A10 G11 I12 A13 E32 K33 R38 G41 Q42 R103 D154 G155 Y265 G286 D287 P294 G299 N300
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0043731 6-hydroxynicotinate 3-monooxygenase activity

View graph for
Molecular Function
External links
PDB RCSB:8twg, PDBe:8twg, PDBj:8twg
PDBsum8twg
PubMed38493211
UniProtA0A222NYA8

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