Structure of PDB 8trq Chain B

Receptor sequence
>8trqB (length=190) Species: 9606 (Homo sapiens) [Search protein sequence]
TRPRFLEQVKHECHFFNGTERVRFLDRYFYHQEEYVRFDSDVGEYRAVTE
LGRPDAEYWNSQKDLLEQKRAAVDTYCRHNYGVGESFTVQRRVYPEVTVY
PAKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKTGVVSTGLIQNGD
WTFQTLVMLETVPRSGEVYTCQVEHPSLTSPLTVEWRAGS
3D structure
PDB8trq T cell recognition of citrullinated alpha-enolase peptide presented by HLA-DR4
ChainB
Resolution2.75 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B E9 H13 F26 Y30 D57 Y60 W61 Q70 K71 Y78 H81 N82 V85 E7 H11 F24 Y28 D55 Y58 W59 Q68 K69 Y76 H79 N80 V83
External links
PDB RCSB:8trq, PDBe:8trq, PDBj:8trq
PDBsum8trq
PubMed39043656
UniProtP01911|DRB1_HUMAN HLA class II histocompatibility antigen, DRB1 beta chain (Gene Name=HLA-DRB1)

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