Structure of PDB 8trl Chain B

Receptor sequence
>8trlB (length=175) Species: 9606 (Homo sapiens) [Search protein sequence]
TRPRFLEQVKHECHFFNGTERVRFLDRYFYHQEEYVRFDSDVGEYRAVTE
LGRPDAEYWNSQKDLLEQKRAAVDTYCRHNYGVGESFTVQRRVYPEVTVY
PALLVCSVNGFYPGSIEVRWFRNGQEEKTGVVSTGLIQNGDWTFQTLVML
ETVEVYTCQVEHPSLTSPLTVEWRA
3D structure
PDB8trl T cell recognition of citrullinated alpha-enolase peptide presented by HLA-DR4
ChainB
Resolution2.4 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B H13 F26 Y30 P56 D57 Y60 W61 Q70 K71 Y78 H81 N82 V85 H11 F24 Y28 P54 D55 Y58 W59 Q68 K69 Y76 H79 N80 V83
External links
PDB RCSB:8trl, PDBe:8trl, PDBj:8trl
PDBsum8trl
PubMed39043656
UniProtP01911|DRB1_HUMAN HLA class II histocompatibility antigen, DRB1 beta chain (Gene Name=HLA-DRB1)

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