Structure of PDB 8trd Chain B

Receptor sequence
>8trdB (length=733) Species: 10116 (Rattus norvegicus) [Search protein sequence]
IKIEGDLVLGGLFPINEKGTGTEECGRINEDRGIQRLEAMLFAIDEINKD
NYLLPGVKLGVHILDTCSRDTYALEQSLEFVRASLTKVEQENIPLLIAGV
IGGSYSSVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDF
YQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFEQEARLRNICIATAE
KVGRSNIRKSYDSVIRELLQKPNARVVVLFMRSDDSRELIAAANRVNASF
TWVASDGWGAQESIVKGSEHVAYGAITLELASHPVRQFDRYFQSLNPYNN
HRNPWFRDFWEQKFQCSLQQVCDKHLAIDSSNYEQESKIMFVVNAVYAMA
HALHKMQRTLCPNTTKLCDAMKILDGKKLYKEYLLKINFTAPFNPDSIVK
FDTFGDGMGRYNVFNLQYSYLKVGHWAETLSLDVDSIHWSRNSVPTSQCS
DPCAPNEMKNMQPGDVCCWICIPCEPYEYLVDEFTCMDCGPGQWPDLSGC
YNLPYKWEDAWAIGPVTIACLGFLCTCIVITVFIKGRELCYILLFGVSLS
YCMTFFFIAKPSPVICALRRLGLGTSFAICYSALLTKTNCIAISPSSQVF
ICLGLILVQIVMVSVWLILETPGTRRYTLPEKRETVILKCNVKDSSMLIS
LTYDVVLVILCTVYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFY
VTSSDYRVQTTTMCISVSLSGFVVLGCLFAPKV
3D structure
PDB8trd Structural basis of allosteric modulation of metabotropic glutamate receptor activation and desensitization
ChainB
Resolution3.4 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 Z99 B R64 R68 S149 Y150 S151 A172 S173 T174 Y222 D301 K389 R32 R36 S104 Y105 S106 A127 S128 T129 Y177 D256 K338
External links
PDB RCSB:8trd, PDBe:8trd, PDBj:8trd
PDBsum8trd
PubMed39090128
UniProtP31422|GRM3_RAT Metabotropic glutamate receptor 3 (Gene Name=Grm3)

[Back to BioLiP]