Structure of PDB 8tpp Chain B

Receptor sequence
>8tppB (length=584) Species: 660122 (Fusarium vanettenii 77-13-4) [Search protein sequence]
SNFGVDFVIHYKVPAAERDEAEAGFVQLIRALTTVGLATEVRHGENESLL
VFVKVASPDLFAKQVYRARLGDWLHGVRVSAQALQDEPVVEAERLRLIYL
MITKPHNEGGAGVTPTNAKWKHVESIFPLHSHSFNKEWIKKWSSKYTLEQ
TDIDNIRDKFGESVAFYFAFLRSYFRFLVIPSAFGFGAWLLLGQFSYLYA
LLCGLWSVVFFEYWKKQEVDLAVQWGVRGVSSIQQSRPEFEWEHEAEEPV
KVYPPMKRVKTQLLQIPFALACVVALGALIVTCNSLEVFINEVLPTIFLV
IGTPTISGVLMGAAEKLNAMENYATVDAHDAALIQKQFVLNFMTSYMALF
FTAFVYIPFGHILHPFLNFWRFQINPAAISNQMFYFTVTAQIVNFATEVV
VPYIKQQAFQKEEAEFLQRVREECTLEEYDVSGDYREMVMQFGYVAMFSV
AWPLAACCFLVNNWVELRSDALKIAISSRRPIPWRTDSIGPWLTALSFLS
WLGSITSSAIVYLCSNKAWGLLLSILFAEHFYLVVQLAVRFVLSKLSPGL
QKERKERFQTFWQRQRGMQETIEIGRRMIEQQLA
3D structure
PDB8tpp Structural basis of closed groove scrambling by a TMEM16 protein.
ChainB
Resolution3.64 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B E452 D503 E506 E535 D539 E398 D434 E437 E466 D470
BS02 CA B N448 E506 E535 N394 E437 E466
Gene Ontology
Molecular Function
GO:0005254 chloride channel activity
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0032541 cortical endoplasmic reticulum

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8tpp, PDBe:8tpp, PDBj:8tpp
PDBsum8tpp
PubMed38684930
UniProtC7Z7K1

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